The appearance of your fingernails can change with certain medical conditions. Kidney disease is associated with multiple distinctive nail problems. A buildup of nitrogen waste products occurs in the bodies of people with kidney disease, which can lead to changes in finger and toenails.

The kidneys filter waste from the blood and maintain the right balance of fluid in the body. They also play an important role in regulating blood pressure. In general, people with impaired kidney function are advised to eat a diet that supports healthy blood pressure and good blood sugar control.